8608. Sodium Dibunate

Nomenclature

CAS number: 14992-59-7
2,6-Bis(1,1-dimethylethyl)-1-naphthalenesulfonic acid sodium salt; L-1633; 1633 Labaz; Becantal; Becantex; Dibunafon; Keuten; Linctussal.
C18H23NaO3S; mol wt 342.43.
C 63.13%, H 6.77%, Na 6.71%, O 14.02%, S 9.36%.

Description and references

Although most sources refer to this compound as sodium 2,6-di-tert-butylnaphthalene sulfonate, it is a mixture of at least two isomers. Prepn and separation of isomers: Menard et al., Can. J. Chem. 39, 729 (1961).

Chemical structure

Properties

Slightly hygroscopic crystals, dec >300°. Slightly sol in cold water (0.5-1.0%); freely sol in hot water; sol in methanol, less sol in ethanol. Aq solns are stable to boiling.

Therapeutic Category

Antitussive.

Keywords

Antitussive