Nomenclature
CAS number: 149-44-0
Hydroxymethanesulfinic acid sodium salt; formaldehyde sodium sulfoxylate; formaldehydesulfoxylic acid sodium salt; sodium hydroxymethanesulfinate; sodium methanalsulfoxylate; Aldanil; Rongalite; Rongalite C.
CH
3NaO
3S; mol wt 118.09.
C 10.17%, H 2.56%, Na 19.47%, O 40.65%, S 27.15%.
Na[HOCH
2SO
2].
Description and references
Prepn: Heyl, Greer, Am. J. Pharm. 94, 80 (1922); Binns, US 2013125 (1935 to Virginia Smelting); Postnikov, Kunin, J. Appl. Chem.
USSR 13, 185 (1940). Structure of dihydrate:
Truter, J. Chem. Soc. 1955, 3064; 1962, 3400. Of limited value in treatment of mercuric
chloride poisoning: Modell et al., J. Pharmacol. Exp. Ther. 61, 66 (1937).
Derivative
Dihydrate.
Properties
Crystals, mp 63-64°, dec at higher temp. Odorless when freshly prepd,
but quickly develops a characteristic (garlic) odor. Freely sol in
water; practically insol in abs alcohol, ether, benzene. Readily
dec by dil acids. Aq soln is practically neutral. Keep well closed in a cool place. LD s.c. in mice, 4.0 g/kg: Rosenthal, Public Health Rep. 49, 908 (1934).Use
In vat color printing pastes: Borstelmann, Fordemwalt,
US 2597281 (1952 to Am. Cyanamid). In polymerization of ethylenic compds:
GB 816252;
GB 852593 (1959 to Hercules Powder; 1960 to Air Reduction). In manuf of arsphenamines: Krumwiede,
J. Am. Pharm. Assoc. 8, 795 (1919); Heyl,
Miller,
ibid. 11, 432
(1922).
Therapeutic Category
Treatment of mercury poisoning.