8666. Sodium Polyanetholesulfonate

Nomenclature

CAS number: 52993-95-0
Polyanetholesulfonic acid sodium salt; anetholesulfonic acid sodium salt polymer.

Description and references

A polymer of anetholesulfonic acid. Originally developed as an anticoagulant, it was soon found that it possesses anticomplement action and lowers the bactericidal action of blood. Ref: Demole, Reinert, Arch. Exp. Pathol. Pharmakol. 158, 211 (1930); Friedmann, Klin. Wochenschr. 14, 215 (1935); Stuart, J. Clin. Pathol. 1, 311 (1948).

Chemical structure

Properties

Light brown powder. Insol in alcohol. Swells in water and slowly goes in soln with neutral reaction. Aq solns are stable to heat, dil alkalies and dil acids.

Use

To inhibit blood coagulation in vitro, and as diagnostic reagent to encourage the growth of pathogens in blood. To stabilize colloidal solns such as milk and gelatin.