8673. Sodium Selenite

Nomenclature

CAS number: 10102-18-8
Selenious acid disodium salt; Selenase (Biosyn).
Na2O3Se; mol wt 172.94.
Na 26.59%, O 27.75%, Se 45.66%.
Na2SeO3.

Description and references

Prepd by evaporating an aqueous solution of sodium hydroxide and selenious acid between 60° and 100°: Krak, J. Am. Ceram. Soc. 12, 530 (1929); by heating a mixture of sodium chloride and selenium oxide: Cameron, Macallan, Proc. Roy. Soc. 46, 13 (1890). Metabolism: M. Sandholm, Acta Pharmacol. Toxicol. 33, 6 (1973); H. W. Symonds et al., Br. J. Nutr. 45, 117 (1981). Mutagenicity study: M. Nodo et al., Mutat. Res. 66, 175 (1979). Toxicity study: Cummins, Kimura, Toxicol. Appl. Pharmacol. 20, 89 (1971). Clinical effect of selenium supplementation on immune cell function: M. Roy et al., Biol. Trace Elem. Res. 46, 115 (1994); L. Kiremidjian-Schumacher et al., ibid. 183. Clinical evaluation as immunostimulant in head and neck cancer: eidem, ibid. 73, 97 (2000); in treatment of radiation-associated secondary lymphedema: O. Micke et al., Int. J. Radiat. Oncol. Biol. Phys. 56, 40 (2003).

Properties

Tetragonal prisms. Stable in air. Freely sol in water. Insol in alcohol. LD50 orally in rats: 7 mg/kg (Cummins, Kimura).

Use

Removing green color from glass during its manuf; alkaloidal reagent.

Therapeutic Category

Selenium supplement.

Therapeutic Category (Veterinary)

Selenium supplement for livestock.

Keywords

Replenishers/Supplements; Selenium