8694. Sodium Thiosulfate

Nomenclature

CAS number: 7772-98-7
Thiosulfuric acid (H2S2O3) sodium salt (1:2); sodium hyposulfite; “hypo”; antichlor; Sodothiol; Sulfothiorine; Ametox.
Na2O3S2; mol wt 158.11.
Na 29.08%, O 30.36%, S 40.56%.
Na2S2O3.

Description and references

Review of mfg processes: Faith, Keyes & Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 769-773. Crystal structure of the pentahydrate: A. A. Uraz, N. Armagan, Acta Crystallogr. B33, 1396 (1977). Toxicity of the pentahydrate: C. Voegtlin et al., J. Pharmacol. Exp. Ther. 25, 297 (1925).

Properties

Powder. Sol in water; practically insol in alcohol.

Derivative

Pentahydrate.

Nomenclature

CAS number: 10102-17-7
Na2O3S2.5H2O; mol wt 248.18.
Na 18.53%, O 51.57%, S 25.84%, H 4.06%.

Properties

Odorless crystals or granules, mp 48° when rapidly heated. Effloresces in warm dry air; slightly deliquesces in moist air. d 1.69. Loses all its water at 100°; dec at higher temp. Sol in water; insol in alcohol. Slowly dec in aq soln at ordinary temp, more rapidly when heated. The aq soln is practically neutral. pH 6.5-8.0. It dissolves silver halides and many other salts of silver. Incompat: Iodine, acids; lead, mercury, and silver salts. LD i.v. in rats: >2.5 g/kg (Voegtlin).

Use

To remove chlorine from solns according to the eq: Na2S2O3 + 4Cl2 +5H2O → 2NaHSO4 + 8HCl and Na2S2O3 + 2HCl → 2NaCl + H2O + S + SO2. As “antichlor” in bleaching of paper pulp; as fixer in photography; for extraction of silver from ores; as mordant in dyeing and printing textiles; reducer in chrome dyeing; manuf leather; bleaching bone, straw, ivory; also as titrimetry reagent in analytical chemistry.

Therapeutic Category

Antidote (cyanide).

Therapeutic Category (Veterinary)

Antidote (cyanide). Has been used as a “general detoxifier”, in bloat, and externally in ringworm, mange.

Keywords

Antidote (Cyanide)