8788. Stannous Pyrophosphate

Nomenclature

CAS number: 15578-26-4
Diphosphoric acid tin(2+) salt (1:2); ditin diphosphate; ditin pyrophosphate.
O7P2Sn2; mol wt 411.36.
O 27.23%, P 15.06%, Sn 57.72%.
Sn2P2O7.

Description and references

Prepd by thermal dehydration of stannous hydrogen phosphate: Jablczynski, Wieckowski, Z. Anorg. Allg. Chem. 152, 207 (1926); from Na2H2P2O7 and SnCl2: Klement, Haselbeck, Ber. 96, 1022 (1958); from pyrophosphoric acid and stannous chloride: Nelson, US 3401012 (1968 to Monsanto). Clinical application for labelling red blood cells: D. Ducasson et al., Br. J. Radiol. 49, 344 (1976). Chemical characterization of technetium complexes: J. Kroesbergen et al., Nucl. Med. Biol. 15, 209 (1988). Diagnostic application in bone scanning: N. S. Anderton et al., Am. J. Roentgenol. Radium Ther. Nucl. Med. 124, 625 (1975); in myocardial infarction: D. E. Jansen et al., Circulation 75, 611 (1987).

Properties

Amorphous powder. d16.4 4.009. Insol in water. Sol in concd acid, excess alkali.

Derivative

99mTechnetium complex.

Nomenclature

99mTc-PPi; 99mTc-PYP; TechneScan PYP (Mallinckrodt).

Use

Ingredient in caries-preventing toothpaste: Norris, Schweizer, US 2946725 (1960 to Proctor & Gamble).

Therapeutic Category

99mTc complex as diagnostic aid (radioactive imaging agent).

Keywords

Stannous Pyrophosphate Complex with 99mTc: Diagnostic Aid (Radioactive Imaging Agent)