8900. Sulfachlorpyridazine
Nomenclature
CAS number: 80-32-0
4-Amino-N-(6-chloro-3-pyridazinyl)benzenesulfonamide; N1-(6-chloro-3-pyridazinyl)sulfanilamide; 3-chloro-6-sulfanilamidopyridazine; 3-sulfanilamido-6-chloropyridazine; 3-(p-aminophenylsulfonamido)-6-chloropyridazine; Ciba 10370; Ba-10370; Cosumix (Novartis); Sonilyn (Carter-Wallace). C10H9ClN4O2S; mol wt 284.72.
C 42.18%, H 3.19%, Cl 12.45%, N 19.68%, O 11.24%, S 11.26%.
Description and references
Prepn: Lester, English, US 2790798 (1957 to Am. Cyanamid). Comparative antibacterial spectrum: G. E. Burrows et al., J. Vet. Diagn. Invest. 5, 541 (1993). Pharmacokinetics and therapeutic potential in horses: E. van Duijkeren et al., Vet. Rec. 137, 483 (1995). ELISA determn in food of animal origin: C. A. Spinks et al., Food Addit. Contam. 18, 11 (2001).
Derivative
Sodium salt.Nomenclature
CAS number: 23282-55-5
Vetisulid (Fort Dodge). C10H8ClN4NaO2S; mol wt 306.70.
C 39.16%, H 2.63%, Cl 11.56%, N 18.27%, Na 7.50%, O 10.43%,
S 10.45%.
Therapeutic Category
Antibacterial.
Therapeutic Category (Veterinary)
Antibacterial agent. In enteric infections.Keywords
Antibacterial (Synthetic); Sulfonamides