8966. Sulfotep

Nomenclature

CAS number: 3689-24-5
Thiodiphosphoric acid tetraethyl ester; thiopyrophosphoric acid tetraethyl ester; sulfotepp; thiotepp; dithio; dithione; dithiophos; TEDP; ASP-47; Bayer E 393; ENT-16273; Bladafum (Bayer).
C8H20O5P2S2; mol wt 322.32.
C 29.81%, H 6.25%, O 24.82%, P 19.22%, S 19.90%.

Description and references

Prepn: A. D. F. Toy, J. Am. Chem. Soc. 73, 4670 (1951); G. Schrader, R. Mühlmann, DE 848812 (1952 to Bayer), C.A. 47, 5426a (1953); R. Appel, H. Einig, Z. Anorg. Allg. Chem. 414, 236 (1975). Activity: F. F. Smith et al., J. Econ. Entomol. 43, 627 (1950). Toxicity data: B. Holmstedt, Pharmacol. Rev. 11, 567 (1959).

Chemical structure

Properties

Pale yellow liquid, bp2 136-139°. Poisonous. Vapor press. at 20°: 1.7 × 104 mm Hg. d425 1.196. nD25 1.4753. Soly in water: 25 mg/l. Miscible with most organic solvents. Corrosive to iron. LD50 s.c. in mice: 8 mg/kg (Holmstedt).

Caution

Potential symptoms of overexposure are eye pain, blurred vision, lacrimation and rhinorrhea; headache; cyanosis; anorexia, nausea, vomiting and diarrhea; local sweating, weakness, twitching, paralysis, Cheyne-Stokes respiration, convulsions, low blood pressure and cardiac irregularities; skin and eye irritation. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 294.

Use

Insecticide; miticide.