Nomenclature
CAS number: 2783-94-0
6-Hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid
disodium salt; 1-
p-sulfophenylazo-2-naphthol-6-sulfonic acid disodium
salt; FD & C Yellow No. 6; C.I. Food Yellow 3; C.I. 15985.
C
16H
10N
2Na
2O
7S
2; mol wt 452.37.
C 42.48%, H 2.23%, N 6.19%, Na 10.16%, O 24.76%, S 14.18%.
Description and references
Prepn: P. Griess, Ber. 11, 2191 (1878). Metabolism: J. L.
Radomski, T. J. Mellinger, J. Pharmacol. Exp.
Ther. 136, 259 (1962). Toxicology: I. F.
Gaunt et al., Food Cosmet. Toxicol. 5, 747 (1967); 7, 9 (1969); 12, 1 (1974). Review: IARC Monographs 8, 257-266 (1967). See also: Colour Index vol. 4 (3rd ed.,
1971) p 4087.
Properties
Orange-red crystals. Absorption
max (0.02 N CH3COONH4): 480 nm. Sol in water;
slightly sol in ethanol. Reddish-orange soln in conc H2SO4, changing to yellow on dilution. LD50 in rats, mice (g/kg): >10, >6 orally (Gaunt, 1967).Use
Provisionally listed for use in food, drugs and
cosmetics.