9080. Tazanolast

Nomenclature

CAS number: 82989-25-1
Oxo[[3-(1H-tetrazol-5-yl)phenyl]amino]acetic acid butyl ester; butyl 3′-(1H-tetrazol-5-yl)oxanilate; TO-188; WP-833; Tazalest (Wakamoto); Tazanol (Wakamoto).
C13H15N5O3; mol wt 289.29.
C 53.97%, H 5.23%, N 24.21%, O 16.59%.

Description and references

Mast-cell degranulation inhibitor. Prepn: JP Kokai 82 11975 (1982 to Wakamoto), C.A. 96, 217856a (1982). Immunopharmacology: M. Agata et al., Jpn. J. Pharmacol. 32, 689 (1982). Series of articles on pharmacology and mechanism of action: Arzneim.-Forsch. 38, 70-92 (1988).

Chemical structure

Therapeutic Category

Antiallergic.

Keywords

Antiallergic