9292. Thialbarbital

Nomenclature

CAS number: 467-36-7
5-(2-Cyclohexen-1-yl)dihydro-5-(2-propenyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione; 5-allyl-5-(2-cyclohexen-1-yl)-2-thiobarbituric acid; 5-(2-cyclohexen-1-yl)-5-allyl-2-thiobarbituric acid; thialbarbitone; Kemithal.
C13H16N2O2S; mol wt 264.34.
C 59.07%, H 6.10%, N 10.60%, O 12.11%, S 12.13%.

Description and references

Prepn: Volwiler, Tabern, US 2153730 (1939 to Abbott).

Chemical structure

Properties

Crystals, mp 148-150°.

Derivative

Sodium salt.
C13H15N2NaO2S; mol wt 286.33.
C 54.53%, H 5.28%, N 9.78%, Na 8.03%, O 11.18%, S 11.20%.

Properties

Pale yellow crystals from methanol, mp 130-132°. Very sol in water, alc. Practically insol in benzene, ether. pH of 2.5% soln in water: 10.5.

Note

This is a controlled substance (depressant): 21 CFR, 1308.13.

Therapeutic Category

Anesthetic (intravenous).

Therapeutic Category (Veterinary)

Anesthetic.

Keywords

Anesthetic (Intravenous)