9312. Thibenzazoline

Nomenclature

CAS number: 6028-35-9
1,3-Dihydro-1,3-bis(hydroxymethyl)-2H-benzimidazole-2-thione; 1,3-bis(hydroxymethyl)-2-benzimidazolinethione; 2-mercaptobenzimidazole-1,3-dimethylol; Thyreocordon (Byk Gulden).
C9H10N2O2S; mol wt 210.25.
C 51.41%, H 4.79%, N 13.32%, O 15.22%, S 15.25%.

Description and references

Prepn: Monti, Venturi, Gazz. Chim. Ital. 76, 365 (1946).

Chemical structure

Properties

Very bitter. mp 160-162°. Soluble dil in alkalies.

Therapeutic Category

Antihyperthyroid.

Keywords

Antihyperthyroid