9323. Thiobutabarbital

Nomenclature

CAS number: 2095-57-0
5-Ethyldihydro-5-(1-methylpropyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione; 5-sec-butyl-5-ethyl-2-thiobarbituric acid; 5-ethyl-5-(1-methylpropyl)-2-thiobarbituric acid; thibutabarbital.
C10H16N2O2S; mol wt 228.31.
C 52.61%, H 7.06%, N 12.27%, O 14.02%, S 14.04%.

Description and references

Prepn: Volwiler, Tabern, US 2153729; US 2153731 (both 1939 to Abbott).

Chemical structure

Properties

Crystals, mp 163-165°.

Derivative

Sodium salt.

Nomenclature

CAS number: 947-08-0
Inactin (Byk Gulden); Brevinarcon (Heyden).
C10H15N2NaO2S; mol wt 250.29.
C 47.99%, H 6.04%, N 11.19%, Na 9.19%, O 12.78%, S 12.81%.

Properties

Crystalline, slightly hygroscopic solid. Readily sol in water.

Note

This is a controlled substance (depressant): 21 CFR, 1308.13.

Therapeutic Category

Anesthetic (intravenous).

Keywords

Anesthetic (Intravenous)