9416. Tiadenol

Nomenclature

CAS number: 6964-20-1
2,2′-[1,10-Decanediylbis(thio)]bisethanol; 2,2′-(decamethylenedithio)diethanol; 1,10-bis(2-hydroxyethylthio)decane; LL-1558; Delipid (Coop. Farm.); Eulip (SIT); Fonlipol (Recordati); Tiaden (Malesci); Tiaterol (Midy).
C14H30O2S2; mol wt 294.52.
C 57.09%, H 10.27%, O 10.86%, S 21.77%.

Description and references

Prepn: Williams, Cossar, US 3021215 (1962 to Eastman Kodak); Lafon, DE 2038836 (1971 to Orsymonde), C.A. 75, 35528d (1971). Series of articles on pharmacology, metabolism, and toxicology: Therapie 27, 395-444 (1972).

Chemical structure

Properties

Crystals, mp 69.5°. uv max (ethanol): 212 nm. Soluble in ethanol, chloroform. Practically insol in water.

Therapeutic Category

Antilipemic.

Keywords

Antilipemic