9420. Tianeptine

Nomenclature

CAS number: 66981-73-5
7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide.
C21H25ClN2O4S; mol wt 436.95.
C 57.72%, H 5.77%, Cl 8.11%, N 6.41%, O 14.65%, S 7.34%.

Description and references

Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Prepn: C. Malen et al., DE 2011806 corresp to US 3758528 (1970, 1973 both to Sci. Union et Cie-Soc. Franc. Rech. Med.). Neuropharmacology study: C. Malen, J. Poignant, Experientia 28, 811 (1972).

Chemical structure

Derivative

Sodium salt.

Nomenclature

CAS number: 30123-17-2
S-1574; Stablon (Ardix).
C21H24ClN2NaO4S; mol wt 458.93.
C 54.96%, H 5.27%, Cl 7.73%, N 6.10%, Na 5.01%, O 13.94%, S 6.99%.

Properties

Solid, mp 180°.

Therapeutic Category

Antidepressant.

Keywords

Antidepressant; Tricyclics