9530. Toluene 2,4-Diisocyanate

Nomenclature

CAS number: 584-84-9
2,4-Diisocyanato-1-methylbenzene; 2,4-diisocyanatotoluene; 2,4-tolylene diisocyanate; TDI; Nacconate 100 (Allied).
C9H6N2O2; mol wt 174.16.
C 62.07%, H 3.47%, N 16.08%, O 18.37%.

Description and references

Usually prepd from toluene-2,4-diamine and phosgene. Review: Astle, Industrial Organic Nitrogen Compounds (New York, 1961) pp 284-313; Faith, Keyes & Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 831-835.

Chemical structure

Properties

Liquid at room temperature. Sharp, pungent odor. mp 19.5-21.5°. d420 liq 1.2244. bp760 251°; bp11 126°. Darkens on exposure to sunlight. Reacts with water with evolution of carbon dioxide. Flash pt, open cup: 132°C (270°F). Misc with alcohol (decompn), diglycol monomethyl ether, ether, acetone, carbon tetrachloride, benzene, chlorobenzene, kerosene, olive oil. Concd alkaline compds such as NaOH or tert-amines may cause run-away polymerization.

Caution

Potential symptoms of overexposure are irritation of eyes, skin, nose and throat; choking, paroxysmal cough; chest pain, retrosternal soreness; nausea, vomiting and abdominal pain; bronchitis, bronchospasm, pulmonary edema; dyspnea, asthma; conjunctivitis, lacrimation; dermatitis, skin sensitization. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 312. See also Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) Section II, p 414. This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-256.

Use

In the manuf of polyurethane foams and other elastomers.