Nomenclature
CAS number: 24017-47-8
Phosphorothioic acid
O,O-diethyl
O-(1-phenyl-1
H-1,2,4-triazol-3-yl) ester; 1-phenyl-3-(
O,O-diethylthionophosphoryl)-1,2,4-triazole;
O,O-diethyl
O-1-phenyl-1
H-1,2,4-triazol-3-yl
phosphorothioate; HOE-2960; Hostathion (Bayer CropSci.).
C
12H
16N
3O
3PS; mol wt 313.31.
C 46.00%, H 5.15%, N 13.41%, O 15.32%, P 9.89%, S 10.23%.
Description and references
Organophosphate insecticide; cholinesterase
inhibitor. Prepn: O. Scherer, H Mildenberger, ZA 6803471; eidem, US 3686200 (1968, 1972 both to Hoechst). Properties and analytical
methods: W. G. Thier et al. Anal. Methods Pestic. Plant Growth Regul. 10, 127 (1978). Immunochromatographic determn
in soil and water: W.-J. Gui et
al., Anal. Biochem. 377, 202 (2008) DOI PubMed. Field studies as insecticide and acaricide:
S. J. B. Hay, Proc. 6th Brit. Crop Prot. Council - Insect. Fungic. 597 (1972). Nematocidal activity: A. Sirohi, Siyanand, Indian J. Nematol. 22, 134 (1992). Residues and dissipation
rates in soil and wheat crops: W. Li et al., Ecotoxicol. Environ. Saf. 69, 312 (2008) DOI PubMed.
Properties
Light brown oil, mp 0-5°. Vapor pressure 2.9 × 106 mbar (303 K). d 1.247. Soly at 296 K: 39 ppm in water. Soly at 298 K (g/100 ml):
n-hexane 0.7, toluene 30, ethyl acetate 30, acetone 30,
ethanol 30. LD50 in rats (mg/kg): 82 orally, 1100 dermally (Thier). LD50 in
rats (mg/kg): 107 i.p.; in rabbits (mg/kg): 280 dermally (Hay).Use
Insecticide; acaricide; nematocide.