9608. Tribenoside

Nomenclature

CAS number: 10310-32-4
Ethyl 3,5,6-tris-O-(phenylmethyl)-d-glucofuranoside; Ba-21401; Alven (Firma); Flebosan (Dukron); Glyvenol (Novartis); Hemocuron (Takeda); Venex (Recordati).
C29H34O6; mol wt 478.58.
C 72.78%, H 7.16%, O 20.06%.

Description and references

Prepn: Druey, Huber, US 3157634 (1964 to Ciba). Pharmacology: Lecomte, C. R. Seances Soc. Biol. Ses Fil. 163, 1469 (1969); Helfer, Jaques, Pharmacology 5, 23 (1971). Increase in capillary resistance in patients with rheumatoid arthritis: W. C. Dick et al., Ann. Rheum. Dis. 28, 187 (1969). GLC determn in plasma: A. Sioufi, F. Pommier, J. Pharm. Sci. 69, 167 (1980). Excretion as hippuric acid: eidem, Eur. J. Drug Metab. Pharmacokinet. 7, 223 (1982). Review of pharmacology: R. Jaques, ibid. 15, 445-460 (1977).

Chemical structure

Properties

bp1.2 270-280°. [α]D26 +8° (chloroform).

Therapeutic Category

Sclerosing agent.

Keywords

Sclerosing Agent