Prepd from ethyl trichloroacetate and aq ammonia, and physical and thermodynamic properties: Davies, Jenkin, J. Chem. Soc. 1954, 2374; by action of phosphorus pentoxide on trichloroacetamide: Carpenter, J. Org. Chem. 27, 2085 (1962) DOI. Manuf by reaction of methylnitrile, HCl and chlorine gas: Kbisch, US 2745868 (1956 to Degussa). Toxicity study: H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 23, 95 (1962) PubMed.