9654. Triclocarban

Nomenclature

CAS number: 101-20-2
N-(4-Chlorophenyl)-N′-(3,4-dichlorophenyl)urea; 3,4,4′-trichlorocarbanilide; 1-(3′,4′-dichlorophenyl)-3-(4′-chlorophenyl)urea; TCC; Cutisan (Boots); Nobacter (Chantereau); Solubacter (Pharmethic).
C13H9Cl3N2O; mol wt 315.58.
C 49.48%, H 2.87%, Cl 33.70%, N 8.88%, O 5.07%.

Description and references

Prepn from 3,4-dichloroaniline and 4-chlorophenyl isocyanate: Beaver et al., J. Am. Chem. Soc. 79, 1236 (1957); Beaver, Stoffel, US 2818390 (1957 to Monsanto); GB 769273 (1957).

Chemical structure

Properties

Fine white plates, mp 255.2-256°.

Use

Bacteriostat and antiseptic in soaps and other cleansing compositions.

Therapeutic Category

Antiseptic, disinfectant.

Keywords

Antiseptic/Disinfectant; Halogens/Halogen Containing Compounds