9777. Tropane

Nomenclature

CAS number: 529-17-9
8-Methyl-8-azabicyclo[3.2.1]octane; 1αH,5αH-tropane; 2,3-dihydro-8-methylnortropidine.
C8H15N; mol wt 125.21.
C 76.74%, H 12.07%, N 11.19%.

Description and references

Structure and synthesis: Ladenburg, Ber. 16, 1408 (1883); Merling, Ber. 25, 3124 (1892); Willsttter, Iglauer, Ber. 30, 721 (1897); 33, 1170 (1900); eidem, Ann. 317, 315, 350 (1901); Robinson, J. Chem. Soc. 111, 762, 876 (1917); Hess, Ber. 51, 1007 (1918); Schpf, Angew. Chem. 50, 779, 797 (1937); Ruggli, Maeder, Helv. Chim. Acta 27, 436 (1944); Keagle, Hartung, J. Am. Chem. Soc. 68, 1608 (1946).

Chemical structure

Properties

Liquid; bp 163-169°; d1515 0.9259. Sparingly sol in water, the soly decreasing with an increase in temp. Tropane and water will mix provided the volume of tropane is in excess.