9782. Tropine Benzylate

Nomenclature

CAS number: 3736-36-5
endo-α-Hydroxy-α-phenylbenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; 1αH,5αH-tropan-3α-ol benzilate; benzilic acid 3α-tropanyl ester; glykin; BAT; BTE; BETE.
C22H25NO3; mol wt 351.44.
C 75.19%, H 7.17%, N 3.99%, O 13.66%.

Description and references

Prepn: Hromatka et al., Monatsh. Chem. 83, 1321 (1952).

Chemical structure

Properties

Prisms from ether or benzene, mp 152-153°.

Derivative

Hydrochloride.
C22H25NO3.HCl; mol wt 387.90.
C 68.12%, H 6.76%, N 3.61%, O 12.37%, Cl 9.14%.

Properties

mp 239-240°.