9799. TSQ

Nomenclature

CAS number: 109628-27-5
N-(6-Methoxy-8-quinolinyl)-4-methylbenzenesulfonamide; 6-methoxy-8-(p-toluenesulfonyl)aminoquinoline.
C17H16N2O3S; mol wt 328.39.
C 62.18%, H 4.91%, N 8.53%, O 14.62%, S 9.76%.

Description and references

Fluorescent membrane permeant probe selective for Zn2+ in the presence of Ca2+ and Mg2+. Prepn: G. B. Bachman et al., J. Org. Chem. 15, 1278 (1950). Atomic absoportion determn of Zn2+ to picomole levels in biological systems: J. G. Reyes et al., Biol. Res. 27, 49 (1994). Structure/mechanism analysis: M. S. Nasir et al., J. Biol. Inorg. Chem. 4, 775 (1999). Visualization of reactive zinc in the brain: C. J. Frederickson et al., J. Neurosci. Methods 20, 91 (1987); in extracellular areas of CNS: A. A. Larson et al., Pain 86, 177 (2000); in apoptosis: G. R. Sauer et al., J. Cell. Biochem. 88, 954 (2003).

Chemical structure

Properties

White crystalline solid from ethanol, mp 133-134°.

Use

Determn of extracellular and intracellular Zn2+ levels in biological systems.