9905. Valeronitrile

Nomenclature

CAS number: 110-59-8
Pentanenitrile; 1-butyl cyanide; 1-cyanobutane.
C5H9N; mol wt 83.13.
C 72.24%, H 10.91%, N 16.85%.
CH3(CH2)3CN.

Description and references

Prepn: A. Lieben, A. Rossi, Ann. 158, 137 (1871); W. Kantlehner et al., ibid. 1980, 389; H. G. Thomas, H. D. Greyn, Synthesis 1990, 129. Acute toxicity and metabolism: H. Tanii, K. Hashimoto, Arch. Toxicol. 55, 47 (1984). Comparative toxicity of aliphatic nitriles: M. A. Wallig et al., Food Chem. Toxicol. 26, 149 (1988).

Properties

bp15 45-47°. bp739.3 140.4°. bp 141°. d0 0.8164. nD20 1.3962. Log P (n-octanol/water): 0.94. LD50 orally in male mice: 2.297 mmol/kg (Tanii).

Use

Solvent.