10009. Viscosin

Nomenclature

CAS number: 27127-62-4
C54H95N9O16; mol wt 1126.38.
C 57.58%, H 8.50%, N 11.19%, O 22.73%.

Description and references

Antibiotic substance produced by Pseudomonas viscosa. Isoln: Kochi et al., Bact. Proc. 1951, 29; Groupé et al., Proc. Soc. Exp. Biol. Med. 78, 354 (1951); Ohno et al., J. Agric. Chem. Soc. Jpn. 27, 665 (1953); C.A. 49, 3012 (1955); Toki, Ohno, C.A. 53, 243b (1959). Synthesis studies: Fukuda, Bani, C.A. 56, 10265i (1962). Structure: Toki, Ohno, loc. cit. Revised structure: Hiramoto et al., Tetrahedron Lett. 1970, 1087; eidem, Chem. Pharm. Bull. 19, 1308, 1315 (1971). Shows antitubercular activity.

Chemical structure

Properties

Powder, dec 270-273°. [α]D29 168.3° (ethanol). Stable to heat. Practically insol in water. Sol in methanol, ethanol, ether, acetone, alkaline phosphate buffer solns.