10128. Zinc Acetate

Nomenclature

CAS number: 557-34-6
Galzin (Lemmon).
C4H6O4Zn; mol wt 183.50.
C 26.18%, H 3.30%, O 34.88%, Zn 35.65%.
Zn(C2H3O2)2.

Description and references

Prepn of anhydr salt from zinc nitrate and acetic anhydride: Spth, Monatsh. Chem. 33, 235 (1912). Clinical evaluations in Wilson's disease: G. M. Hill et al., Hepatology 7, 522 (1987); G. J. Brewer et al., J. Lab. Clin. Med. 109, 526 (1987). Toxicity: H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 30, 470 (1969).

Derivative

Dihydrate.

Nomenclature

CAS number: 5970-45-6
Wilzin (Orphan Europe).
C4H6O4Zn.2H2O; mol wt 219.53.
C 21.88%, H 4.59%, O 43.73%, Zn 29.80%.

Properties

Crystallizes from dil acetic acid; faint, acetous odor; astringent taste; slightly efflorescent. d 1.735; mp 237°. One gram dissolves in 2.3 ml water, 1.6 ml boiling water, 30 ml alcohol, about 1 ml boiling alcohol. The aq soln is neutral or slightly acid to litmus; pH about 5-6. Keep in well-closed containers. LD50 orally in rats: 2.46 g/kg (Smyth).

Use

Preserving wood; as mordant in dyeing; manuf glazes for painting on porcelain. As a reagent in testing for albumin, tannin, urobilin, phosphate, blood.

Therapeutic Category

Styptic, astringent. In treatment of Wilson's disease.

Therapeutic Category (Veterinary)

Antiseptic, astringent, protective (topical). Has been used as an emetic.

Keywords

Astringent; Emetic