10159. Zinc Sulfate

Nomenclature

CAS number: 7733-02-0
White vitriol; zinc vitriol.
O4SZn; mol wt 161.47.
O 39.63%, S 19.86%, Zn 40.51%.
ZnSO4.

Description and references

Prepn and physical properties: Gmelins, Zink (8th ed.) 32, 936-960 (1956). Effects of oral zinc sulfate in acne treatment: G. Michaelsson et al., Arch. Dermatol. 113, 31 (1977). Clinical evaluations in Wilson's Disease: T. U. Hoogenraad, C. J. A. Van den Hamer, Acta Neurol. Scand. 67, 356 (1983); T. U. Hoogenraad et al., J. Neurol. Sci. 77, 137 (1987).

Derivative

Monohydrate.

Nomenclature

CAS number: 7446-19-7
Dried zinc sulfate; Zincaps (RPR); Z Span (Goldshield).

Properties

Powder or granules. Loses H2O above 238°. Sol in water. Practically insol in alcohol.

Derivative

Heptahydrate.

Nomenclature

CAS number: 7446-20-0
Collazin (Vitaplex); Keratol (Streuli); Op-Thal-Zin (Alcon); Redeema (Merz); Solvazinc (Thames); Solvezink (Tika); Virudermin (Robugen); Zincate (Paddock); Zincomed (Schwarz).

Properties

Odorless crystals or granules or powder; astringent taste. Efflorescent in dry air. d 1.97. mp 100°. At 280° loses all H2O; dec above 500°. One gram dissolves in 0.6 ml water, 2.5 ml glycerol. Insol in alcohol. The aq soln is acid to litmus; pH about 4.5. Keep well closed.

Note

The monohydrate does not cake as the heptahydrate does, and hence is more convenient for use during the warm season and in warm climates.

Caution

Irritating to skin, mucous membranes: H. E. Stokinger, Patty's Industrial Hygiene and Toxicology 2A, G. D. Clayton, F. E. Clayton, Eds. (John Wiley & Sons, New York, 1981) pp 2033-2049.

Use

As mordant in calico-printing; preserving wood and skins; with hypochlorite for bleaching paper; manuf lithopone and other zinc salts; clarifying glue; electrodepositing Zn; also as reagent in analytical chemistry.

Therapeutic Category

Ophthalmic astringent. Zinc supplement.

Therapeutic Category (Veterinary)

Astringent. Has been used as an emetic.

Keywords

Astringent; Replenishers/Supplements; Zinc