10198. Zoxamide

Nomenclature

CAS number: 156052-68-5
3,5-Dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-4-methylbenzamide; N-[3′-(1′-chloro-3′-methyl-2′-oxopentan)]-3,5-dichloro-4-methylbenzamide; RH-7281; Zoxium (Dow AgroSci.).
C14H16Cl3NO2; mol wt 336.64.
C 49.95%, H 4.79%, Cl 31.59%, N 4.16%, O 9.51%.

Description and references

Fungicide for foliar use on potatoes, vines and vegetables, targeting Oomycete fungi. Prepn: E. L. Michelotti, D. H. Young, US 5304572 (1994 to Rohm and Haas); H. L. Rayle, L. Fellmeth, Org. Process Res. Dev. 3, 172 (1999). Comprehensive description: A. R. Egan et al., Brighton Crop Prot. Conf. - Pests Dis. 1998, 335-342. Mode of action: D. H. Young, R. A. Slawecki, Pestic. Biochem. Physiol. 69, 100 (2001). Laboratory resistance risk study: D. H. Young et al., Pest Manage. Sci. 57, 1081 (2001).

Chemical structure

Properties

White solid. mp 158-160° (Rayle); also reported as mp 159.5-160.5° (Egan). Log P (octanol/water): 3.76 (20°). Vapor pressure at 25°, 35°, 45°: <1x10-7 torr. Soly at 20° (mg/l): water 0.681. LD50 in rats (mg/kg): >5000 orally; >2000 dermally. LC50 in rats (mg/l): >5.3 by inhalation; in mallard ducks, bobwhite quail (mg/kg): >5250, >5250 dietary; in trout (μg/l): 160 (Egan).

Use

Agricultural fungicide.