12-01195. Berbine [Archived]

Nomenclature

CAS number: 483-49-8
5,8,13,13a-Tetrahydro-6H-dibenzo[a,g]quinolizine; tetrahydroprotoberberine.
C17H17N; mol wt 235.32.
C 86.77%, H 7.28%, N 5.95%.

Description and references

Proposed as parent substance for naming berberine and similar alkaloids: Awe, Arch. Pharm. 270, 156 (1932). Synthesis: Chakravarti et al., J. Chem. Soc. 1927, 2278.

Chemical structure

Properties

Clusters of needles from ether, mp 85°. Strong base, dissolves readily in alcohol, ether. Insol in petr ether.

Status

This monograph has been retired and is no longer subject to revision or update.