12-01499. Bufogenin B [Archived]

Nomenclature

CAS number: 465-19-0
(3β,5β,16β)-3,14,16-Trihydroxybufa-20,22-dienolide; desacetylbufotalin.
C24H34O5; mol wt 402.52.
C 71.61%, H 8.51%, O 19.87%.

Description and references

Isolated from the Chinese drug Ch'an Su which is prepd from Chinese toads (Bufo asiaticus = Bufo gargarizans Cantor); also obtained from bufotalin: Ruckstuhl, Meyer, Helv. Chim. Acta 40, 1270 (1957).

Chemical structure

Properties

Elongated prisms from methanol, begins to sinter at 195°, dec 210-223°. [α]D19 +30° (c = 1.039 in dioxane). Very sparingly sol in chloroform, methanol, acetone.

Status

This monograph has been retired and is no longer subject to revision or update.