12-02606. Corybulbine [Archived]

Nomenclature

CAS number: 518-77-4
5,8,13,13a-Tetrahydro-2,9,10-trimethoxy-13-methyl-6H-dibenzo[a,g]quinolizin-3-ol; 2,9,10-trimethoxy-13-methyl-13a-berbin-3-ol; 3-hydroxy-13-methyl-2,9,10-trimethoxyberbine; Corydalis-G.
C21H25NO4; mol wt 355.43.
C 70.96%, H 7.09%, N 3.94%, O 18.01%.

Description and references

In Corydalis cava (L.) Schweigg & Korte (C. tuberosa DC.); Fumariaceae: Freund, Josephi, Ann. 277, 1 (1893); in C. platycarpa Makino, Fumariaceae: Manske, Can. J. Res. 21B, 13 (1943). Structure: Spth, Dobrowsky, Ber. 58, 1274 (1925).

Chemical structure

Properties

Needles from methanol, mp 242°. [α]D20 +303° (c = 1.4 in CHCl3). Unstable in light. Weakly basic. Sol in acetone, chloroform, hot benzene; sparingly sol in water, alc, ether.

Derivative

Hydrochloride.
C21H25NO4.HCl; mol wt 391.89.
C 64.36%, H 6.69%, N 3.57%, O 16.33%, Cl 9.05%.

Properties

Prisms, dec 245-250°.

Status

This monograph has been retired and is no longer subject to revision or update.