12-03509. Drosophilin A [Archived]

Nomenclature

CAS number: 484-67-3
2,3,5,6-Tetrachloro-4-methoxyphenol; p-methoxytetrachlorophenol.
C7H4Cl4O2; mol wt 261.92.
C 32.10%, H 1.54%, Cl 54.14%, O 12.22%.

Description and references

Antibiotic substance isolated from the basidiomycete Drosophila subatrata (Batsch ex Fr.) Quel., grown in a corn-steep medium: Kavanagh, Hervey, Proc. Natl. Acad. Sci. USA 38, 555 (1952). Prepn from tetrachloro-p-anisidine: Bures, Hutter, Cas. Cesk. Lek. 11, 29, 57 (1931); C.A. 25, 5153; Chem. Zentralbl. 1931, II, 225; from 1,4-dimethoxytetrachlorobenzene: Anchel, J. Am. Chem. Soc. 74, 2943 (1952).

Chemical structure

Properties

Crystals from hexane or dil alcohol, mp 114°. uv max: 301 nm. Sparingly sol in water; sol in hexane, benzene, acetone, alcohol, chloroform, ether.

Status

This monograph has been retired and is no longer subject to revision or update.