12-03727. Erythrophlamine [Archived]

Nomenclature

CAS number: 511-00-2
[1R-(1α,2α,4aα,4bβ,7E,8β,8aα,10aβ)]-7-[2-[2-(Dimethylamino)ethoxy]-2-oxoethylidene]tetradecahydro-2-hydroxy-1,4a,8-trimethyl-9-oxo-1-phenanthrenecarboxylic acid methyl ester.
C25H39NO6; mol wt 449.58.
C 66.79%, H 8.74%, N 3.12%, O 21.35%.

Description and references

Extracted from the bark of Erythrophleum guineense G. Don., and E. couminga Baillon, Leguminosae. Isoln: Ruzicka et al., Experientia 1, 160 (1945); Engel, Tondeur, Helv. Chim. Acta 32, 2364 (1949). Structure: Mathieson et al., Experientia 16, 404 (1960); Arya, Engel, Helv. Chim. Acta 44, 1650 (1961).

Chemical structure

Properties

Crystals from ether + petr ether, mp 149-151°. [α]D20 62.5° (c = 0.911 in alc). uv max: 222 nm (log ε 4.2).

Status

This monograph has been retired and is no longer subject to revision or update.