12-03950. Euprocin [Archived]

Nomenclature

CAS number: 1301-42-4
(8α,9R)-10,11-Dihydro-6′-(3-methylbutoxy)cinchonan-9-ol; hydrocupreine isopentyl ether; isoamylhydrocupreine; isopentylhydrocupreine; eucupine; Eucupin (White).
C24H34N2O2; mol wt 382.54.
C 75.35%, H 8.96%, N 7.32%, O 8.36%.

Description and references

Prepd from hydrocupreine and p-toluenesulfonic acid isopentyl ester: Slotta, Behnisch, Ber. 66, 360 (1933).

Chemical structure

Properties

Almost tasteless powder, mp 152°. Sol in alc, ether, chloroform. Practically insol in water.

Derivative

Dihydrochloride monohydrate.
C24H34N2O2.2HCl.H2O; mol wt 473.48.
C 60.88%, H 8.09%, N 5.92%, O 10.14%, Cl 14.98%.

Properties

Fine bitter needles. Sol in 15 parts water; freely sol in alc.

Therapeutic Category

Anesthetic (local); antiseptic.

Keywords

Anesthetic (Local); Antiseptic/Disinfectant; Quinolines

Status

This monograph has been retired and is no longer subject to revision or update.