12-03995. Fenalamide [Archived]

Nomenclature

CAS number: 4551-59-1
α-[[[2-(Diethylamino)ethyl]amino]carbonyl]-α-ethylbenzeneacetic acid ethyl ester; N-[2-(diethylamino)ethyl]-2-ethyl-2-phenylmalonamic acid ethyl ester; ethyl N-[2-(diethylamino)ethyl]-2-ethyl-2-phenylmalonamate; phenylethylmalonic acid (diethylamino)ethylamide ethyl ester; Spasmamide (Schering AG).
C19H30N2O3; mol wt 334.45.
C 68.23%, H 9.04%, N 8.38%, O 14.35%.

Description and references

Smooth muscle relaxant. Prepn: Galimberti et al., US 3025317 (1962 to Soc. Ital. Prod. Schering).

Chemical structure

Properties

bp3 182-188°. Sol in acetone, methanol, ethanol, ethyl acetate, benzene, chloroform, ether, mineral acids. Practically insol in water, alkalies.

Derivative

Hydrobromide.

Properties

Crystals, dec 74-80°.

Derivative

Hydrochloride.

Properties

Crystals, dec 71-74°.

Therapeutic Category

Antispasmodic.

Keywords

Antispasmodic

Status

This monograph has been retired and is no longer subject to revision or update.