12-04489. Glycarsamide [Archived]

Nomenclature

CAS number: 144-87-6
[4-[(Hydroxyacetyl)amino]phenyl]arsonic acid; N-glycoloylarsanilic acid; N-glycolylarsanilic acid; p-glycolylaminobenzenearsonic acid; p-glycolylaminophenylarsinic acid.
C8H10AsNO5; mol wt 275.09.
C 34.93%, H 3.66%, As 27.24%, N 5.09%, O 29.08%.

Description and references

Prepd by treating arsanilic acid with chloroacetyl chloride and NaOH: Streitwolf et al., DE 513210; GB 344532 (1929 to I. G. Farben).

Chemical structure

Properties

Crystals from dil acid or water, mp 202-203°. Freely sol in hot water, methanol. Sparingly sol in cold water, acetic acid. Practically insol in acetone, benzene.

Derivative

Sodium salt.

Nomenclature

SNGA.
C8H9AsNNaO5; mol wt 297.07.
C 32.34%, H 3.05%, As 25.22%, N 4.71%, Na 7.74%, O 26.93%.

Description and references

Toxicity and physiological disposition: McChesney et al., Toxicol. Appl. Pharmacol. 4, 14 (1962).

Properties

Crystals. Noticeable acid odor. Freely sol in water.

Therapeutic Category (Veterinary)

Anthelmintic (Strongyloidosis).

Status

This monograph has been retired and is no longer subject to revision or update.