12-04564. Gratioside [Archived]

Nomenclature

CAS number: 53762-90-6
C42H68O14; mol wt 796.98.
C 63.30%, H 8.60%, O 28.11%.

Description and references

Triterpene glycoside monohydrate from tubers of Gratiola officinalis L., Scrophulariaceae: Retzlaff, Arch. Pharm. 240, 561 (1902); Tschesche et al., Ann. 674, 196 (1964). Dec on hydrolysis into 1 mol gratiogenin and 2 mol glucose: Tschesche, Heesch, Ber. 85, 1067 (1952).

Derivative

Monohydrate.

Properties

Clusters of crystals from ethanol, mp 268-274°; [α]D20 +75° (c = 0.825 in alc). Also reported mp 286-289°; [α]D21 +81° (c = 0.83 in ethanol), (Tschesche, 1964). uv max (methanol): 295 nm (log ε 1.84). Slightly sol in water, freely in alcohol. Practically insol in ether.

Status

This monograph has been retired and is no longer subject to revision or update.