12-04710. Hetolin (Boehringer, Mann.) [Archived]

Nomenclature

CAS number: 2390-22-9
1-Methyl-4-[3,3,3-tris(4-chlorophenyl)-1-oxopropyl]piperazine; 1-methyl-4-[3,3,3-tris(p-chlorophenyl)propionyl]piperazine; 1-[β,β,β-tris(p-chlorophenyl)propionyl]-4-methylpiperazine; LZ-544.
C26H25Cl3N2O; mol wt 487.85.
C 64.01%, H 5.17%, Cl 21.80%, N 5.74%, O 3.28%.

Description and references

Prepn: BE 634833 (1964 to Hoechst), C.A. 61, 16076h (1964). Pharmacology: M. Schorr et al., Arzneim.-Forsch. 14, 1151 (1964).

Chemical structure

Properties

Crystals from ethyl acetate, mp 213-215°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 1949-07-1
Dicroden.
C26H25Cl3N2O.HCl; mol wt 524.31.
C 59.56%, H 5.00%, Cl 27.05%, N 5.34%, O 3.05%.

Properties

Crystals from ethanol, mp 267-269°. Freely sol in hot water and alcohol.

Therapeutic Category (Veterinary)

Anthelmintic (flukicide).

Status

This monograph has been retired and is no longer subject to revision or update.