12-04945. Imiclopazine [Archived]

Nomenclature

CAS number: 7224-08-0
1-[2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethyl]-3-methyl-2-imidazolidinone; 3-chloro-10-[γ-[N′-[β-(1-methyl-2-oxoimidazolidin-3-yl)ethyl]-N-piperazinyl]propyl]phenothiazine; chlorimpiphenine.
C25H32ClN5OS; mol wt 486.07.
C 61.77%, H 6.64%, Cl 7.29%, N 14.41%, O 3.29%, S 6.60%.

Description and references

Prepn: BE 668972 (1965 to Asta), C.A. 65, 8934f (1966).

Chemical structure

Properties

Free base, bp0.01 260°.

Derivative

Dihydrochloride.

Nomenclature

CAS number: 7414-95-1
P-4241; Ponsital.
C25H32ClN5OS.2HCl; mol wt 558.99.
C 53.72%, H 6.13%, Cl 19.03%, N 12.53%, O 2.86%, S 5.74%.

Properties

Crystals from dioxane or aq acetone.

Therapeutic Category

Antipsychotic.

Keywords

Antipsychotic; Phenothiazines

Status

This monograph has been retired and is no longer subject to revision or update.