12-05994. Metaxalone [Archived]

Nomenclature

CAS number: 1665-48-1
5-(3,5-Dimethylphenoxymethyl)-2-oxazolidinone; AHR-438; Skelaxin (Robins).
C12H15NO3; mol wt 221.25.
C 65.14%, H 6.83%, N 6.33%, O 21.69%.

Description and references

Prepn: Lunsford et al., J. Am. Chem. Soc. 82, 1166 (1960); Lunsford, US 3062827 (1962 to A. H. Robins).

Chemical structure

Properties

Crystals from ethyl acetate, mp 121.5-123°.

Therapeutic Category

Muscle relaxant (skeletal).

Keywords

Muscle Relaxant (Skeletal)

Status

This monograph has been retired and is no longer subject to revision or update.