12-09027. Styramate [Archived]

Nomenclature

CAS number: 94-35-9
1-Phenyl-1,2-ethanediol 2-carbamate; carbamic acid β-hydroxyphenethyl ester; 2-phenyl-2-hydroxyethyl carbamate; 2-hydroxy-2-phenylethyl carbamate.
C9H11NO3; mol wt 181.19.
C 59.66%, H 6.12%, N 7.73%, O 26.49%.

Description and references

Prepn: GB 841626; C. D. Bossinger, K. G. Taylor, US 3265728 (1960, 1966 both to Armour). Pharmacology: De Salva et al., J. Pharmacol. Exp. Ther. 126, 318 (1959).

Chemical structure

Properties

Crystals from chloroform, mp 111-112°. LD50 orally in mice: 1240 mg/kg (De Salva).

Status

This monograph has been retired and is no longer subject to revision or update.