12-10129. Vintiamol [Archived]

Nomenclature

CAS number: 26242-33-1
N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(3-oxo-3-phenyl-1-propenyl)thio]-1-butenyl]formamide; N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[2-[(2-benzoylvinyl)thio]-4-hydroxy-1-methyl-1-butenyl]formamide; S-(benzoylvinyl)thiamine.
C21H24N4O3S; mol wt 412.51.
C 61.14%, H 5.86%, N 13.58%, O 11.64%, S 7.77%.

Description and references

Prepn and sepn of isomers: Fusco, Tenconi, Farmaco Ed. Sci. 20, 866 (1965).

Chemical structure

Properties

Higher melting isomer: crystals from ethanol, mp 202- 204°, very sparingly sol in chloroform. Lower melting isomer: separated from mixture of both isomers by its greater soly in chloroform; crystals from ethanol contg 1 molecule of ethanol, mp 100-103°.

Status

This monograph has been retired and is no longer subject to revision or update.