13-02093. Chlorbetamide [Archived]

Nomenclature

CAS number: 97-27-8
2,2-Dichloro-N-[(2,4-dichlorophenyl)methyl]-N-(2-hydroxyethyl)acetamide; 2,2-dichloro-N-(2,4-dichlorobenzyl)-N-(2-hydroxyethyl)acetamide; N-(2,4-dichlorobenzyl)-N-(2-hydroxyethyl)dichloroacetamide; Win-5047; Mantomide (Winthrop); Pontalin.
C11H11Cl4NO2; mol wt 331.02.
C 39.91%, H 3.35%, Cl 42.84%, N 4.23%, O 9.67%.

Description and references

Prepn: Surrey, J. Am. Chem. Soc. 76, 2214 (1954); US 2732402 (1956 to Sterling Drug).

Chemical structure

Properties

Crystals from benzene + Skellysolve A, mp 112.4-113.4°. Slightly bitter taste. Very slightly sol in water; sol in 95% ethanol to at least 5%.

Therapeutic Category

Antiamebic.

Keywords

Antiamebic

Status

This monograph has been retired and is no longer subject to revision or update.