13-02735. Cyclexanone [Archived]

Nomenclature

CAS number: 15301-52-7
2-(1-Cyclopenten-1-yl)-2-[2-(4-morpholinyl)ethyl]cyclopentanone; 2-(Δ-1′-cyclopentenyl)-2-(β-tetrahydroparoxazinoethyl)cyclopentanone; 1-(β-N-morpholinoethyl)-1-cyclopentenylcyclopentane-2-one; pentethylcyclanone.
C16H25NO2; mol wt 263.38.
C 72.96%, H 9.57%, N 5.32%, O 12.15%.

Description and references

Prepd from 2-cyclopentylidenecyclopentanone and N-(β-chloroethyl)morpholine: Ueberwasser, DE 1059901; GB 878677 (l959, l961 both to Ciba).

Chemical structure

Properties

Liquid, bp0.035 112°.

Derivative

Hydrochloride.
C16H25NO2.HCl; mol wt 299.84.
C 64.09%, H 8.74%, N 4.67%, O 10.67%, Cl 11.82%.

Properties

Crystals from aq ethanol, mp 209°.

Derivative

Methiodide.
C16H25NO2.CH3I; mol wt 405.31.
C 50.38%, H 6.96%, N 3.46%, O 7.89%, I 31.31%.

Properties

Crystals, mp 106°.

Therapeutic Category

Antitussive.

Keywords

Antitussive

Status

This monograph has been retired and is no longer subject to revision or update.