13-02803. Cyproquinate [Archived]

Nomenclature

CAS number: 19485-08-6
6,7-Bis(cyclopropylmethoxy)-4-hydroxy-3-quinolinecarboxylic acid ethyl ester; ethyl 6,7-bis(cyclopropylmethoxy)-4-hydroxyquinoline-3-carboxylate; cyproquinidate; cyproxyquine; Su-18137; Coxytrol (Squibb).
C20H23NO5; mol wt 357.40.
C 67.21%, H 6.49%, N 3.92%, O 22.38%.

Description and references

Prepn by ring closure of corresp dialkyl (alkoxyphenylamino)methylenemalonates: Mizzoni et al., Experientia 24, 1188 (1968); Mizzoni, DeStevens, ZA 6705655 (1968 to Ciba), C.A. 70, 47316t (1969). Review of structure and biology: Mizzoni et al., J. Med. Chem. 13, 870 (1970).

Chemical structure

Properties

Crystals from DMF, mp 288-288.5° (dec).

Therapeutic Category (Veterinary)

Coccidiostat.

Status

This monograph has been retired and is no longer subject to revision or update.