13-03331. Dioxaphetyl Butyrate [Archived]

Nomenclature

CAS number: 467-86-7
α,α-Diphenyl-4-morpholinebutanoic acid ethyl ester; ethyl 4-morpholino-2,2-diphenylbutyrate; 4-morpholino-2,2-diphenylbutyric acid ethyl ester; Amidalgon; Spasmoxal(e).
C22H27NO3; mol wt 353.45.
C 74.76%, H 7.70%, N 3.96%, O 13.58%.

Description and references

Prepn: Specter et al., J. Am. Chem. Soc. 71, 57 (1949); Dupré et al., J. Chem. Soc. 1949, 500; Bockmühl, Ehrhart, US 2230774 (1940 to Winthrop).

Chemical structure

Derivative

Hydrochloride.
C22H27NO3.HCl; mol wt 389.92.
C 67.77%, H 7.24%, N 3.59%, O 12.31%, Cl 9.09%.

Properties

mp 168-169°.

Note

This is a controlled substance (opiate): 21 CFR, 1308.11.

Therapeutic Category

Analgesic (narcotic). Antispasmodic.

Keywords

Analgesic (Narcotic); Antispasmodic

Status

This monograph has been retired and is no longer subject to revision or update.