13-03367. Diphetarsone [Archived]

Nomenclature

CAS number: 515-76-4
[1,2-Ethanediylbis(imino-4,1-phenylene)]bis[arsonic acid] disodium salt; N,N′-ethylenediarsanilic acid disodium salt; bis[p-arsonophenylamino]-1,2-ethane disodium; N,N′-bis(p-arsonophenyl)ethylenediamine disodium; RP-4763; Amebarsin; Bémarsal (Specia); Rodameb (Specia).
C14H16As2N2Na2O6; mol wt 504.11.
C 33.36%, H 3.20%, As 29.72%, N 5.56%, Na 9.12%, O 19.04%.

Description and references

Prepn: Hamilton, J. Am. Chem. Soc. 45, 2751 (1923).

Chemical structure

Derivative

Decahydrate.

Properties

Powder, no definite melting range. Freely sol in water; slightly sol in boiling 95% ethanol. Practically insol in abs ethanol, acetone, chloroform. pH of a 2% aq soln: 6 to 8. Precipitated from aq solns by acids.

Therapeutic Category

Antiamebic.

Keywords

Antiamebic

Status

This monograph has been retired and is no longer subject to revision or update.