13-04527. Glypinamide [Archived]

Nomenclature

CAS number: 1228-19-9
4-Chloro-N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]benzenesulfonamide; 1-(p-chlorophenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea; azepinamide; Parinase (Upjohn).
C13H18ClN3O3S; mol wt 331.82.
C 47.06%, H 5.47%, Cl 10.68%, N 12.66%, O 14.47%, S 9.66%.

Description and references

Orally active, sulfonylurea hypoglycemic agent. Prepn: Wright, GB 887886 (1962 to Upjohn); Wright, Willette, J. Med. Pharm. Chem. 5, 815 (1962).

Chemical structure

Properties

Crystals from methyl ethyl ketone, mp 197-198.5°.

Therapeutic Category

Antidiabetic.

Keywords

Antidiabetic; Sulfonylurea Derivatives

Status

This monograph has been retired and is no longer subject to revision or update.