13-04740. Histapyrrodine [Archived]

Nomenclature

CAS number: 493-80-1
N-Phenyl-N-(phenylmethyl)-1-pyrrolidineethanamine; 1-[2-(N-benzylanilino)ethyl]pyrrolidine; N-pyrrolidylethyl-N-phenylbenzylamine; N-benzyl-N-phenylpyrrolidinoethylamine; N-benzyl-N-pyrrolidinoethylaniline.
C19H24N2; mol wt 280.41.
C 81.38%, H 8.63%, N 9.99%.

Description and references

Prepn: Hopff et al., US 2623880 (1952). Chemical properties: Auterhoff, Arch. Pharm. 284, 123 (1951).

Chemical structure

Properties

bp1 198-205°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 6113-17-3
Calcistin (Galenus); Domistan (Servier); Luvistin (Boehringer, Ing.).
C19H24N2.HCl; mol wt 316.87.
C 72.02%, H 7.95%, N 8.84%, Cl 11.19%.

Properties

Crystals from alc, mp 196-197°. Soly in water (18°): 2 g/100 ml.

Therapeutic Category

Antihistaminic.

Keywords

Antihistaminic; Ethylenediamine Derivatives

Status

This monograph has been retired and is no longer subject to revision or update.