13-05357. p-Lactophenetide [Archived]

Nomenclature

CAS number: 539-08-2
N-(4-Ethoxyphenyl)-2-hydroxypropanamide; p-lactophenetidide; lactyl-p-phenetidin-N-(p-ethoxyphenyl)lactamide; Fenolactine; Lactophenin; Phenolactine.
C11H15NO3; mol wt 209.24.
C 63.14%, H 7.23%, N 6.69%, O 22.94%.

Description and references

Prepn: Shapiro et al., J. Am. Chem. Soc. 81, 6322 (1959).

Chemical structure

Properties

Slightly bitter crystals from ethyl acetate + hexane, mp 117-118°. One gram dissolves in 330 ml cold, 55 ml boiling water, 8.5 ml alcohol; slightly sol in ether, petr ether.

Therapeutic Category

Analgesic, antipyretic.

Keywords

Analgesic (Non-Narcotic); Antipyretic

Status

This monograph has been retired and is no longer subject to revision or update.